Cryodepleted plasma

It contains most clotting factors in similar amounts to FFP but is deficient in factor VIII, fibrinogen, von Willebrand factor (the high molecular weight multimers are more thoroughly removed than the smaller multimers), factor XIII and fibronectin.

Cryodepleted plasma has a shelf life of 12 months when stored at –25˚ C or below.


Typical unit content and specifications

The typical unit content data is derived from Lifeblood process control testing. For each parameter, the mean value (± 1 SD) and specification is shown.

Unless otherwise specified, data is for the period 1 January to 31 December 2023.


Cryodepleted plasma whole blood

Volume (mL)247 ± 13 (215–265)


Cryodepleted plasma apheresis

Volume (mL)757 ±10 (675–825)



Cryodepleted plasma is available in all ABO groups. Matching for RhD type is not required.  



There is no modification available for cryodepleted plasma. Matching for RhD type is not required.