Cryodepleted plasma is used as an alternative to fresh frozen plasma (FFP) for plasma exchange in patients with thrombotic thrombocytopenic purpura (TTP).
None.
Volume depends on local plasma exchange protocols and the patient’s weight with a 10–15 mL/kg dose usually recommended.
Cryodepleted plasma should be ABO compatible with the recipient's red cells. Matching for RhD type is not required.
Updated July 2026